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Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid CAS 378-44-9

Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid CAS 378-44-9

    • Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid  CAS 378-44-9
    • Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid  CAS 378-44-9
    • Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid  CAS 378-44-9
  • Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid  CAS 378-44-9

    Product Details:

    Place of Origin: China
    Brand Name: Shucan
    Certification: SGS,ISO9001
    Model Number: 378-44-9

    Payment & Shipping Terms:

    Minimum Order Quantity: 10gram
    Price: 1~3USD
    Packaging Details: discreet and safe foil bag or tin
    Delivery Time: within 5 working days after the payment
    Payment Terms: West Union, T/T, Money Gram.,Bitcorn and bank transfer
    Supply Ability: 5000kilogram per month
    Detailed Product Description
    Name: Betamethasone Delivery Time: WITHIN 24 HOURS AFTER YOUR PAYMENT
    Purity: 99%min Key Words: Betamethasone
    Appearance: White Powder CAS: 378-44-9
    E-MAIL: Hathaway@shucanpharm.com

    Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid CAS 378-44-9

     

    Basic information:

    Product Name: Betamethasone

     

    Synonyms: (11beta,16beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;16-beta-methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20;16-beta-Methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20-dione;17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-9-alpha-fluoro-11-bet;6beta)-;9-alpha-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione;9-alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-beta-methylpregna-1,4-diene;9-alpha-fluoro-16-beta-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20
    CAS: 378-44-9
    MF: C22H29FO5
    MW: 392.46
    EINECS: 206-825-4
    Product Categories: Mol File: 378-44-9.mol

    Chemical Properties:

    MP 235-237°C
    refractive index 118 ° (C=1, Dioxane)
    storage temp. 0-6°C
    Merck 1180
    CAS DataBase Reference 378-44-9(CAS DataBase Reference)


     

    Description:

    Betamethasone, dexamethasone of isomers, the role and purpose with dexamethasone acetate, the sodium and water retention effect and dose than the latter is small. Glucose metabolism and anti-inflammatory effect than hydrocortisone strong as hydrocortisone 15 times, but the effect of sodium retention hydrocortisone hundred times more, in primary adrenal hypofunction in with glucocorticoid steroid replacement therapy used together. Also suitable for low renin and low aldosterone syndrome, autonomic neuropathy induced orthostatic hypotension. Because of the goods taken orally is prone to cause edema, more topically applying topical treatment for seborrheic eczema, contact dermatitis, anal, genital itching embolism. Mainly used for allergic and autoimmune inflammatory diseases. It is used for activities rheumatism, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, but also for the comprehensive treatment of certain infections.


     

    Application:

    1. Betamethasone is a corticosteroid used as a topical cream to relieve skin irritation, such as itching and flaking from eczema. It is used as a treatment for local psoriasis, as betamethasone dipropionate and
    salicylic acid, or as the combination betamethasone/calcipotriol. Betamethasone sodium phosphate is
    used orally and via injection with the same indications as other steroids.


    2. Betamethasone is also used prior to delivery of a preterm baby to help prepare the lung for breathing

     

    COA:

     

    Identification (B,C) Complies with the Standard Complies
    Specific optical Rotation +118°~+126° +123.5°
    Single impurity Not more than 1.0% 0.29%
    impurity that ≥0.5% Not more than one Complies
    total impurities Not more than 2.0% 0.64%
    Loss on drying Not more than 1.0% 0.05%
    Assay(UV, basis on drying) 97.0%~103.0% 98.8%
    Methanol Not more than 3000ppm Complies
    Ethyl acetate Not more than 5000ppm Complies
    Acetone Not more than 5000ppm Complies
    DMF Not more than 880ppm Complies
    Dichloromethane Not more than 600ppm Complies
    Chloroform Not more than 60ppm Complies
    Particle Size 100.0%<30um Complies
    Residue on ignition Not more than 0.2% 0.03%
    Conclusion Qualified


     

    Safety Information:

    Hazard Codes Xi,Xn,T
    Risk Statements 40-48/20/21-61
    Safety Statements 22-36-45-53
    RTECS TU4000000
    HS Code 29379000
    Hazardous Substances Data 378-44-9(Hazardous Substances Data)


     

    Usage And Synthesis:

    Chemical Properties White to Off-White Solid
    Usage Betamethasone is a glucocorticoid used as an anti-inflammatory agent. immunosuppressive

     

     

    Phar Raw Materials Betamethasone Corticosteroids Anti Inflammatory Glucocorticoid  CAS 378-44-9

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