Shanghai Shucan Industrial Co.,Ltd
|Place of Origin:||China|
|Minimum Order Quantity:||10gram|
|Packaging Details:||discreet and safe foil bag or tin|
|Delivery Time:||Within 12hours after payment|
|Payment Terms:||West Union, T/T, Money Gram.,Bitcorn and bank transfer|
|Supply Ability:||5000kilogram per month|
|Appearance::||Light Solid Powder||Polciy::||Re-Shipping Policy|
|Delivery::||About 5 Workingdays 100% Door To Door||Packing:||Safe And Discreet Package|
|After-sales Service:||Warm After-sale Service For You 24/7.||Skype:||Mxy0305|
topical anesthetic drugs,
local anesthetic agents
Prilocaine 721-50-6 White Local Anesthetic Drugs Powder lidocaine For Numb Tissue
Product Name: Prilocaine
Synonyms: 2-(propylamino)-o-propionotoluidid;2-(Propylamino)-o-propionotoluidide;2-Methyl-alpha-propylaminopropionanilide;alpha-n-Propyl-amino-2-methylpropionanilide;alpha-n-propylamino-2-methylpropionanilide;Astra 1512;Astra 1515;astra1512
Product Categories: Active Pharmaceutical Ingredients;Inhibitors
Mol File: 721-50-6.mol
It is a kind of needle-like crystals with the melting point being 37-38 ℃ and the boiling point being 159-162 ℃ (0.133kPa), and refractive index (nD20) being 1.5299. Its hydrochloride ([1786-81-8]) is a white crystalline powder. The Melting point is 167-168 ℃. It is soluble in water and ethanol, slightly soluble in chloroform. It has sour taste and bitter taste and is odorless.
Application It is a kind of local anesthetic drug. The product has better efficacy than procaine and the local anesthesia intensity and speed being similar as lidocaine but with longer duration time and less toxicity as well as smaller accumulation effect. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.
Usage And Synthesis:
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.
[Pharmacological] its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6 ~ 7min and the duration time of about 1.5 ~ 2h. It has a strong penetration capability through mucous membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
[Adverse reactions] once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
[Note] patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.
Usage and dosage:
infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
Q how can I be sure the powder contains right substances?
S We can offer you the cretificate of analysis of products and HPLC,Besides, After Receiving the goods, you can send it to detect, or buy a test kit steroid, detect it yourself.
Q What's the guarantees that you will send items after payment
S The feedback of customers:
Tracking Number :DHL3292172505
Yes,i have recieved it,really fast,good job,thanks.
-----Jean from France
We are regular company, we guarantee that after the receipt of your payment we will arrange the shipment within 24 hours , and provide the tracking number, you can keep track of it.so,don't hesitate to let me serve you.
Q What kind of payments does you support?
S T/T, , Money Gram and Bitcion are accepted.
Q What’s the MOQ?
S Generally speaking, the MOQ is 10 gram, but we also can provide you samples for quality inspection.
Q Do you charge for the samples?
S According to our company policy, we just charge the samples based on EXW price. And we will return the samples fee during the next order.
Q Can you packing according to customers' requirements ?
S Sure,we will adopt safe and discreet package.If you have a request for packing, please tell us,Any good ideas are welcomed.
Q Can you tell me your main customers?
S That's our customer’s privacy, we should protect their information.
At the same time, please rest assured that your information is also safe here.
We'll offer you the quotation as soon as possible once receive your inquiry, so pls add my skype(mxy0305) or send E-mail(firstname.lastname@example.org) to me, Start our cooperation!
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