Shanghai Shucan Industrial Co.,Ltd
|Place of Origin:||Shanghai,China|
|Minimum Order Quantity:||5 Grams|
|Packaging Details:||10g/50g/100g/1000g/foil bag|
|Delivery Time:||Within 12hours after payment|
|Payment Terms:||, D/A, D/P, T/T, MoneyGram,Bitcoin|
|Name:||AICAR/ Acadesine||Delivery Time:||WITHIN 24 HOURS AFTER YOUR PAYMENT|
|Purity:||99% Min||Key Words:||Acadesine,AICAR, Acadesine Powder|
|E-MAIL:||Hathaway@shucanpharm.com||Usage:||Pharmaceutical Raw Materials.|
selective androgen receptor modulator,
Aicar / Acadesine Ampk Activator Sarms Powder Prohormone Steroids CAS 2627-69-2
Product Name: AICAR/ Acadesine
|Related substance (HPLC)||Total impurity ≤0.5%
Max single impurity ≤0.1%
|Sieve analysis||100% pass 80 mesh||Complies|
|Loss on Drying
Residue on Ignition
|Total Plate Count||<1000cfu/g||Complies|
|Yeast & Mold||<100cfu/g||Complies|
AICAR (5-aminoimidazole-4-carboxamide-1--D-ribofuranoside, 5-aminoimidazole-4-carboxamide ribonucleoside, acade A number of examples will follow showing AICAR doses uses in research studies, results from treatment, and approximate human equivalent doses, assuming an about-200 lb (90 kg) human for illustration
In "AMPK and PPARdelta agonists are exercise mimetics":Mice, of a strain which is genetically susceptible to obesity and diabetes, were administered AICAR at 500 mg/kg daily for 5 weeks. Their endurance capacity increased by 44%, and expression of 32 genes favorable to metabolism was increased.
Human equivalent dosing would be about 3.2 grams per day, or about 64 vials of product as commonly sold. An example cost of this many 50 mg vials (current as of 2014) would be about $1500.
In "AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats":
Rats were injected subcutaneously once with AICAR at 250 mg/kg. Improvement in whole bodyinsulinsensitivity both post-injection and at the 24 hour point was comparable to what occurs when a bout of exercise is performed rather than an AICAR injection being given.Human equivalent dosing would, again, be about 3.2 grams per day.
In "The Full Capacity of AICAR to Reduce Obesity-Induced Inflammation and Insulin Resistance Requires Myeloid SIRT1":Both lean and diet-induced-obese mice were administered AICAR at 150 mg/kg daily for 5 weeks. For the lean mice AICAR provided no effect on fat mass or insulin sensitivity, but significant improvement did occur for the diet-induced-obese mice. (Interestingly, the improvement was shown to be associated with reduction of the inflammatory cytokines TNF, IL-6, and MCP-1, and required the presence of SIRT1, just as an aside, but it helps make sense of the article title.)Human equivalent dosing would be about 1 gram daily.Other studies may be found, but dosings will be similar to the above.
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