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98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory

98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory

    • 98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory
    • 98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory
    • 98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory
    • 98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory
    • 98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory
  • 98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory

    Product Details:

    Place of Origin: China
    Brand Name: Shucan
    Certification: SGS,ISO9001,ISO9004,USP
    Model Number: 147098-20-2

    Payment & Shipping Terms:

    Minimum Order Quantity: 10gram
    Price: Negotiable
    Packaging Details: discreet and safe foil bag or tin
    Delivery Time: Within 12hours after payment
    Payment Terms: West Union, T/T, Money Gram.,Bitcorn and bank transfer
    Supply Ability: 5000kilogram per month
    Contact Now
    Detailed Product Description
    Appearance:: White To Off-White Crystalline Solid Product Name: Rosuvastatin Calcium
    MF:: C44H54CaF2N6O12S2 Molecular Weight:: 1001.14
    Packing: Safe And Discreet Package After-sales Service: Warm After-sale Service For You 24/7.
    Assay: 98%

    98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Raw Materials For Antiinflammatory

     

    Rosuvastatin calcium

     

    Basic information:

     

    Product Name: Rosuvastatin calcium
    Synonyms: ROSUVASTATIN, CALCIUM SALT;ROSUVASTATIN CALCIUM;ROSUVASTATIN CA;CRESTOR;(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Heptenoic calcium;RosuvastatinCalcium&Z7,Z8,R3;7-{4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid;Rosuvastatin Calium
    CAS: 147098-20-2
    MF: C44H54CaF2N6O12S2
    MW: 1001.14
    Product Categories: Active Pharmaceutical Ingredients;Statins’Anti-Lipidemia Agents;Intermediates & Fine Chemicals;Pharmaceuticals;Rosuvastatin;HMG-COA reductase, Hypolipidemic drugs;rosuvastatin calcium R;API;Aromatics;Chiral Reagents;Sulfur & Selenium Compounds;DERMATOP;Inhibitors
    Mol File: 147098-20-2.mol

     

    Chemical Properties:

     

    MP 122°C
    Appearance White to Off-White Crystalline Solid
    storage temp. -20°C Freezer

     

     

    Usage And Synthesis:

     


    1.A selective, competitive HMG-CoA reductase inhibitor. Antilipemic.antiinflammatory, glucocorticoid
    2.Anti-hyperlipidemia drugs
    Rosuvastatin calcium is an anti-hyperlipidemia drug which belongs to the inhibitor of HMG-CoA reductase successfully developed by the British AstraZeneca company. It is suitable for the treatment of various lipid abnormalities, including hypercholesterolemia, mixed lipid qualitative abnormalities and simple hypertriglyceridemia. Rosuvastatin calcium is listed as the strongest and the most comprehensive statins drugs which has entered into market for lipid-lowering and adjustment. Compared with atorvastatin which is currently recognized with the world's best efficacy, it has a better effect of lowering the level of LDL cholesterol and increasing the level of high-density lipoprotein. Moreover, it has a better tolerance, lower side effects and unique pharmacokinetic characteristics with the half-life about 20h. It only needs to be taken once a day.

     

    Indications:

     

    Primary Hypercholesterolemia:

    Usual dose of rosuvastatin calcium (10 mg) can significantly reduce LDLC levels in patients of primary hypercholesterolemia, and has a better efficacy compared with atorvastatin calcium (10mg). At the end of the experiment, TC, TG levels drop even more. Moreover, 5 mg of rosuvastatin calcium within the same eight weeks of treatment has a better effect on reducing LDLC level compared with 10 mg atorvastatin calcium. The difference is statistically significant, suggesting that the lipid-lowering effect of rosuvastatin calcium is better than that of atorvastatin calcium. Our experimental results are also consistent with the other previous assessment (STELLAR, MERCURY) about efficacy studies on statin drugs. Rosuvastatin calcium has a stronger LDLC-lowering effect than the other statins drugs (atorvastatin, simvastatin and pravastatin), allowing more patients to achieve recommended treatment goals.
    Elderly coronary heart disease combined hyperlipidemia:

    Rosuvastatin calcium is capable of competitively inhibiting liver methylglutaryl coenzyme A reductase, and further exerts its good effect on reducing the fat. It has a long half-life. The gender and age of patients have no significant effect on the metabolism of drugs. The drug has only a few of adverse reactions. Meanwhile, the drug can also effectively promote the transport of low-density lipoprotein into cells, thus improving the cleaning effect of LDL, and playing a role in effectively lowering LDL. In addition, rosuvastatin calcium may also inhibit the aggregation of platelet, reduce the body's inflammatory response and protect their endothelial cells, effectively stabilize the plaque of patients suffering coronary artery disease to reduce its impact on the patient. The patients of experimental group in our hospital were treated with rosuvastatin calcium, which gives a significantly better lipid-lowering effect than patients in the control group, P <0.05, the difference was statistically significant. This further illustrates the usage of rosuvastatin calcium for treatment of elderly coronary heart disease combined hyperlipidemia has a good effect which can improve efficacy, reduce the blood fat with high clinical significance.

     

     

    FAQ:

     

     

    Q how can I be sure the powder contains right substances?
    S  We can offer you the cretificate of analysis of products and HPLC,Besides, After Receiving the goods, you can send it to detect, or buy a test kit steroid, detect it yourself.
    Q What's the guarantees that you will send items after payment
    S The feedback of customers:
    Tracking Number :DHL3292172505
    Yes,i have recieved it,really fast,good job,thanks.
    -----Jean from France
    We are regular company, we guarantee that after the receipt of your payment we will arrange the shipment within 24 hours , and provide the tracking number, you can keep track of it.so,don't hesitate to let me serve you.
    Q What kind of payments does you support?
    S T/T, Western Union, Money Gram and Bitcion are accepted.
    Q What’s the MOQ?
    S Generally speaking, the MOQ is 10 gram, but we also can provide you samples for quality inspection.
    Q Do you charge for the samples?
    S According to our company policy, we just charge the samples based on EXW price. And we will return the samples fee during the next order.
    Q Can you packing according to customers' requirements ?
    S Sure,we will adopt safe and discreet package.If you have a request for packing, please tell us,Any good ideas are welcomed.
    We'll offer you the quotation as soon as possible once receive your inquiry, so pls add my skype(mxy0305) or send E-mail(lareina@shucanpharm.com) to me, Start our cooperation!

     

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    98% Rosuvastatin calcium 147098-20-2 Pharmaceutical Grade For Antiinflammatory

    Contact Details
    Shanghai Shucan Industrial Co.,Ltd

    Contact Person: lareina

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