99% White Anti Estrogen Steroids Powder Chlormadinone Acetate 302-22-7 As Oral Contraceptive

99% Progesteron Steroid Powder Chlormadinone Acetate
 
Features
 
Chlormadinone acetate
CAS: 302-22-7
Standard: CP2000, JP13
Appearance: White or slightly yellow crystalline powder
Assay: 99%
Packing:Foil bag
-----99% Progesteron Steroid Powder Chlormadinone Acetate----------
Product Description
Basic Description:
99% High Quality White or Slightly Yellow Crystalline Powder Chlormadinone Acetate 302-22-7
Chlormadinone acetate
Synonyms: 17-(Acetyloxy)-6-chloropregna-4, 6-diene-3, 20-dione
CAS: 302-22-7
MF: C23H29ClO4
MW: 404.93
Standard: CP2000, JP13
Appearance: White or slightly yellow crystalline powder
Assay: 99%
Packing: Foil bag
Usage: Orally active progesteron with antiandrogenic activity; Has been used in combinations as an oral contraceptive. Progestogen; Antineoplastic (hormonal)
 
Product description:
 
Chlormadinone acetate (INN, USAN, BAN, JAN; Sold under brand names including Clordion, Gestafortin, Lormin, Non-Ovlon, Normenon, Verton, and many others), sometimes abbreviated as CMA, is a steroidal progestin with additional antiandrogen and antigonadotropic (and thus also antiestrogenic) effects. It is used clinically as a hormonal contraceptive, and in part due to its lowering of estrogen levels, but also for improved effectiveness in contraception, chlormadinone is frequently combined with ethinyl estradiol for this purpose. It is the acetate ester of chlormadinone
 
 
Specifications:
 
TEST ITEMS SPECIFICATION RESULTS
Description White or Almost White Crystalline Powder white powder
Identification A.B. Positive
Assay 97.0~102.0% 99.3%
Specific Rotation +101°~+105° +102.6°
Loss On Drying 1.0%max 0.27%
Melting Point 153~157°C 153.0~155.0°C
Organic Volatile Impurities meets the requirement. Conforms
Related Substances meets the requirement. Conforms
Residual Solvents meets the requirement. Conforms
Particle Size 100% ≤ 20 microns Conforms
Conclusion The specification conform with USP30 standard
 
Usage
 
Similarly to other 17-hydroxyprogesterone derivatives such as cyproterone acetate, medroxyprogesterone acetate, and megestrol acetate, chlormadinone acetate is a weak glucocorticoid, and has the potential to cause adrenal insufficiency upon abrupt discontinuation of the drug at sufficient dosages.
 
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